Microwave assisted solventless synthesis of melamines with flexible aromatic substituents

Microwave-assisted flexible synthesis of 7-azaindoles.

7-Azaindoles are versatile building blocks, especially in medicinal chemistry, where they serve as bioisosteres of indoles or purines. Herein, we are presenting a robust and flexible synthesis of 1,3- and 1,3,6-substituted 7-azaindoles starting from nicotinic acid derivatives or 2,6-dichloropyridine, respectively. Microwave heating dramatically accelerates the penultimate reaction step, an epox...

Microwave-assisted synthesis of molybdenum oxide nanoparticles

This paper focused on a simple approach for synthesis of molybdenum oxide (MoO3) nanoparticles and reports a facile route for synthesis of such nanoparticles, using microwave irradiation as a homogenous and powerful source of heating, using ethylene glycol as the solvent and heating medium. For more investigations, besides microwave heating, the obtained solutions were also treated by conventio...

Microwave Assisted Organic Synthesis

Microwave Assisted Synthesis of N-Benzylenaminones Catalyzed by Chloroacetic acid

Benzylaminoalkenones and benzylaminoalkenoates 3 were synthesized from reaction of benzylamine with corresponding 1,3-diketones and 1,3-ketoesters in the presence of catalytic amount of chloroacetic acid under microwave radiation. This method offers several advantages including high yield of products, recyclable of the catalyst and easy experimental work-up procedure.

Ammonium chloride catalyzed microwave-assisted synthesis of tetrahydrobenzo[b]pyrans

In the present work, we have developed a mild, efficient, and environmentally benign method for the synthesis of tetrahydrobenzo[b]pyran derivatives via a three-component cyclocondensation of aldehydes, malononitrile and dimedone utilizing ammonium chloride as a simple, easily available and cost effective catalyst under microwave irradiation. This method has several attracting features such as ...